The research to 1) study Khon Kaen University curriculum qualification framework 2) study problems of Khon Kaen University curriculum process 3) analyze Khon Kaen University curriculum consistency based on TQF. Target groups used in the study included the first 50 questionnaires returned back to the researcher within 2 week and 20 curriculums which failed to pass the curriculum quality assessment in the academic year 2015. The data was collected from key informants consisted of curriculum chairmen/curriculum administrative committee, academic service staff/curriculum-related staff. There are two types of research tools: 1) a questionnaire, 2) an analysis form of the consistency of the curriculum according to the national standard for higher education. The research found that the programme specification process is time-consuming so the development of the curriculum was delayed. There is also a lack of cooperation from teachers who do not agree with the curriculum framework. At the some time there are some personnel reach the retirement age, some are on study leave. No substitute has been appointed to replace these staff.