This research aimed 1) to create and develop a conceptual framework of influencing educational effectiveness of graduate diploma program in teaching profession of College of Asian Scholars 2) to verify the hypothesis of the causal relationship between factors in influencing educational effectiveness of graduate diploma program in teaching profession of College of Asian Scholars and 3) to evaluate and confirm the causal relationship between factors influencing educational effectiveness of graduate diploma program in teaching profession of College of Asian Scholars. In this research, purposive sampling was used as a sampling method by having 178 of student teachers, 162 of Teacher trainer, 162 of school Administrators, 6 of College of Asian Scholars teachers and 3 of curriculum teacher as a sample group. The instrument used in the study included a questionnaire with a rating Scale(5 levels).This questionnaire was separated into 6 parts; first part was the general information of respondents, second was about leadership factors with 15 questions, third part was learning organization factors with 15 questions, forth part was organization engagement factors with 15 questions, fifth part was motivation factors with 15 questions and the final part was organizational effectiveness factors with40questions. The maximum and minimum of arithmetic mean were 4.77 and 4.67 higher than the determined criteria at 3.00 as well as standard deviation which was in the range of 0.37-0.51. The research results indicated as follows: 1) A Causal Model of Factors Influencing Educational Effectiveness of Graduate Diploma Program in Teacher Profession of College of Asian Scholars including of 5 components namely leadership, learning organization, organization engagement and motivation factors and organizational effectiveness with the total factors of 25. 2) The correlation of a causal model of factors influencing educational effectiveness of Graduate Diploma Program in Teacher Profession of College of Asian Scholars was Statistically significant at the 0.05 level for all of 5 components and 25 factors which can be implied that all factors is proper to be applied in this Causal Model with good result. Other statistic numbers were Chi-square at 49.631, df at 14.377 , P-value at 0.071,CFI at 0.910 ,TLI at 0.930, RMSEA at 0.045 and SRMR at 0.048. 3) A causal model of factors influencing educational effectiveness of graduate diploma in teacher profession of College of Asian Scholars was presented in connoisseurship and got positive feedbacks from experts in propriety standards, feasibility standards, accuracy standards, and utility standards. Propriety standards was at the high level (xˉ = 4.56), Feasibility standards was at the high level (xˉ = 4.44), Accuracy standards was at the high level (xˉ = 4.56), utility standards standard was at the high level (xˉ = 4.53). Therefore, it can be implied that this model is reliable and practical.