The purposes of this study were to develop and test the efficiency and achievement of a self-learning on food sanitation’s guideline for restaurants in Nong Hoi Sub-district, Mueang District, Chiang Mai Province. This research and development model used based on ADDIE MODEL. The samples were restaurant executive 42 people in Nong Hoi Sub-district. The tool was Megui Gen's standard self-study series performance test and learning achievement test. Data were analyzed using descriptive statistics and compared learning achievement differences with Wilcox on signed rank test. The results were as follows: Self-developed learning packages were effectiveness as followed the Megui Gen's standards which was equal to 1.32. The learning achievement was found that the mean of the post-test scores was significantly higher than the pre-test scores (P-value ≤ 0.001). This research concluded that the self learning package developed can be used to educate food handlers on how to effectively implement food sanitation.